N Shinomiya Selected Research

3- ((2- nitroimidazol- 1- yl)methoxy)butane- 1,2- 4- triol

2/2000

PR-000350, a novel hypoxic radiosensitizer, enhances tumor cell killing by promoting apoptosis preferentially in the S-phase fraction.

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N Shinomiya Research Topics

Disease

10	Neoplasms (Cancer) 01/2021 - 01/2000
3	Stomach Neoplasms (Stomach Cancer) 11/2000 - 01/2000
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 12/2011
2	Ovarian Neoplasms (Ovarian Cancer) 01/2017 - 02/2015
2	Carcinoma (Carcinomatosis) 06/2014 - 02/2001
2	Gout 12/2011 - 12/2011
2	Bacterial Infections (Bacterial Infection) 02/2007 - 01/2006
2	Infections 01/2006 - 04/2005
2	Bruton type agammaglobulinemia 03/2001 - 12/2000
1	Chronic Renal Insufficiency 01/2018
1	Acute Kidney Injury (Acute Renal Failure) 12/2011
1	Urolithiasis 12/2011
1	Glut1 Deficiency Syndrome 12/2011
1	Renal hypouricemia 12/2011
1	Necrosis 03/2007
1	Hepatitis 03/2007
1	Shwartzman Phenomenon (Shwartzman Reaction) 03/2007
1	Escherichia coli Infections 01/2006
1	Listeriosis (Listeria Infection) 04/2005
1	Carcinogenesis 12/2001
1	Small Cell Carcinoma 02/2001
1	Colorectal Neoplasms (Colorectal Cancer) 01/2001
1	Aneuploidy (Aneuploid) 01/2001
1	Colonic Neoplasms (Colon Cancer) 11/2000
1	Choriocarcinoma 01/2000

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 01/2017 - 11/2000
4	Telomerase (Telomerase Reverse Transcriptase)IBA 12/2001 - 01/2000
3	Interleukin-12 (IL 12)IBA 02/2007 - 04/2005
2	PlatinumIBA 02/2015 - 06/2014
2	Uric Acid (Urate)IBA 12/2011 - 12/2011
2	InterferonsIBA 03/2007 - 01/2006
2	InterleukinsIBA 03/2007 - 01/2006
2	Interleukin-4 (Interleukin 4)IBA 03/2007 - 01/2006
2	CytokinesIBA 03/2007 - 01/2006
2	Interleukin-18 (Interleukin 18)IBA 01/2006 - 04/2005
1	IodineIBA 01/2021
1	Uremic ToxinsIBA 01/2018
1	CaspasesIBA 02/2015
1	Apoptosis Regulatory ProteinsIBA 06/2014
1	Small Interfering RNA (siRNA)IBA 06/2014
1	Cisplatin (Platino)FDA LinkGeneric 06/2014
1	Arginine (L-Arginine)FDA Link 12/2011
1	Adenosine Triphosphate (ATP)IBA 12/2011
1	AnionsIBA 12/2011
1	NucleotidesIBA 12/2011
1	alpha-galactosylceramideIBA 03/2007
1	Concanavalin AIBA 03/2007
1	LipopolysaccharidesIBA 03/2007
1	Interleukin-15 (Interleukin 15)IBA 02/2007
1	Interleukin-2 (IL2)IBA 02/2007
1	Penicillins (Penicillin)FDA Link 02/2007
1	Interleukin-10 (Interleukin 10)IBA 01/2006
1	Immunoglobulin M (IgM)IBA 01/2006
1	Interleukin-13IBA 01/2006
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 03/2001
1	telomerase RNA (bTR)IBA 02/2001
1	A-Form DNA (A-DNA)IBA 01/2001
1	Agammaglobulinaemia Tyrosine KinaseIBA 12/2000
1	Messenger RNA (mRNA)IBA 11/2000
1	4- (4- cyclohexyl- 2- methyloxazol- 5- yl)- 2- fluorobenzenesulfonamideIBA 11/2000
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 11/2000
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 11/2000
1	Dinoprostone (PGE2)FDA Link 11/2000
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 11/2000
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 11/2000
1	Urokinase Plasminogen Activator ReceptorsIBA 11/2000
1	NucleosidesIBA 02/2000
1	3- ((2- nitroimidazol- 1- yl)methoxy)butane- 1,2- 4- triolIBA 02/2000
1	azomycinIBA 02/2000
1	LuciferasesIBA 01/2000

Therapy/Procedure

3	Drug Therapy (Chemotherapy) 01/2017 - 02/2001
2	Injections 03/2007 - 01/2006
2	Radiotherapy 02/2001 - 02/2000
1	Splenectomy 04/2005
1	Aftercare (After-Treatment) 11/2000
1	Therapeutics 02/2000